Arsenic Leukemia Treatment Side Effects

In clinical studies the most commonly reported side effects with atra tretinoin arsenic trioxide are shown here.

Arsenic leukemia treatment side effects.

Arsenic poisoning or arsenicosis occurs after the ingestion or inhalation of high levels of arsenic. Small red or purple spots on the skin. Some forms of arsenic might cause an abnormal heart beat. Common side effects of trisenox include.

In adults with newly diagnosed apl that is low risk. Common adverse reactions to arsenic trioxide include leukocytosis gastrointestinal side effects eg nausea vomiting diarrhea abdominal pain fatigue edema hyperglycemia dyspnea and cough. Side effects not requiring immediate medical attention. Swelling of the abdominal or stomach area.

A note about side effect percentages liver dysfunction 63 heart rhythm abnormalities 16. Acute promyelocytic leukemia apl in patients whose cancer has a certain type of chromosome mutation that affects the pml gene and rara gene. Loss of bowel or bladder control. Ringing in the ears.

Ringing in the ears. Arsenic trioxide is approved to be used with tretinoin to treat. Other side effects not listed may also occur in some patients. Trisenox arsenic trioxide is a cancer medication used to treat a cancer of the blood and bone marrow called acute promyelocytic leukemia or apl.

Medications that can cause an irregular heartbeat qt interval prolonging drugs interacts with arsenic. Chemo or mylotarg is more likely to be included in treatment if this risk is higher. Injection site reactions pain redness or swelling. Coping with side effects.

There have been a few reports of people developing a second cancer some years after arsenic trioxide treatment. If you notice any other effects check with your healthcare professional. Atra plus ato is often the preferred treatment in people at lower risk of the leukemia coming back as it tends to have fewer side effects. There isn t enough information to work out how often this side effect might happen.

It is not clear whether this was due to the arsenic or not. A bone marrow biopsy is usually done about a month after starting treatment to see if the leukemia is in remission. Small red or purple spots on the skin. Swelling of the abdominal or stomach area.

Loss of bowel or bladder control.